War Against the Germs: Epidemics, Microorganisms, and Biowarfare
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  • PART I. INTRODUCTION
    CHAPTER 1.THE GREAT EPIDEMIC BATTLES

     

    Bubonic Plague

    Smallpox 

    Tuberculosis 

    Malaria 

    Influenza Virus

    HIV/AIDS 

    Yellow Fever 

    Polio 

    Cholera 

    Hepatitis C 

    Measles 

    Ebola

    Zika 

    Coronavirus – SARS, MERS, and COVID-19 

    Why do some diseases die out while others become endemic?

     

    CHAPTER 2. THE NOT-SO-GREAT BIOWARFARE BATTLES

      

    PART II. KNOW YOUR GERM ENEMY

    CHAPTER 3. GERM STRATEGY

               Germ Size and Number

                 Bacterial Structure 

                 Viral Structure

    COVID-19
    Protozoan, Worm, and Prion Structures

     

    CHAPTER 4. WEAPONS THAT GERMS USE 

    Weapons that Bacteria Use

    Weapons that Viruses Use

    Weapons that Protozoans and Helminths Use

    Weapons that Fungi Use

    Bacteriophages

     

     

    PART III. KNOW YOURSELF 

    The Human Strategy 

     

    CHAPTER 5. THE IMMUNE SYSTEM
                  Innate (natural) Immunity

    Cells of Innate Immunity
    Molecules of Innate Immunity 
                 Adaptive (Acquired) Immunity
    Humoral (antibody-mediated) Immunity (B-lymphocytes) 

                                        Monoclonal Antibodies
     
                                       Primary and Secondary Response 

                  Cell-mediated Immunity (T-lymphocytes) 

                  When Things Go Wrong
    Microorganism Adaptation
    Insufficient Immune Response

    Excessive Immune Response (Cytokine Storm)

     

    CHAPTER 6. ANTIMICROBIAL DRUGS 

                 Antibiotics
                 Antiviral Drugs
                 Antiprotozoan Drugs
                 Antihelminth Drugs
                 Antifungal Drugs
                 Drug Resistance 

     

    CHAPTER 7. ACTIVE AND PASSIVE IMMUNIZATION

    Active Immunization (Vaccination)

                             “Hey, does the COVID vaccine really work!? I got COVID again, even after taking the booster shot!”
                         
    Future Vaccines
                         
    Why by now don’t we have a vaccine for every type of invading organism?

                Passive Immunization (Antibodies)
                Immunosuppression

     

    CHAPTER 8. ALLEVIATING THE PATIENT’S SYMPTOMS

     

    CHAPTER 9. PERSONAL AND COMMUNITY PREVENTIVE ACTIONS

                How effective are masks?
                Contact Tracing
                How effective are lockdowns? 

     

    PART IV. BIOWARFARE 

                Category A, B, and C Diseases

     

    CHAPTER 10. BIOWARFARE OFFENSE STRATEGY 

                Biological Weapons
                Chemical Weapons
                Cyber Weapons 

     

    CHAPTER 11. BIOWARFARE DEFENSE STRATEGY 

                Government Measures
                Treatment Strategy
                Should bioweapons research be banned?
                Final Thoughts 

     

    CHAPTER 12. LABORATORY TESTING FOR ANTIGEN AND ANTIBODY

                Sensitivity vs. Specificity
                Testing for Antigen

                     What does a positive antigen test mean?
                  
    What does a negative antigen test mean? 

                Testing for Antibody

                     What does a positive antibody test mean?
                     What does a negative antibody test mean? 

     

    APPENDIX I. DNA REPLICATION, TRANSCRIPTION,
    AND TRANSLATION 


    CHAPTER 13. DNA REPLICATION 

               What is a protein?
               What is a gene?
               Mitosis
               Replication of DNA 

     Transposons and Plasmids


      CHAPTER 14. TRANSCRIPTION OF DNA INTO RNA 

               Introns 

     

    CHAPTER 15. TRANSLATION OF RNA INTO PROTEINS 

               Protein Function
               Protein Modification

     

    APPENDIX II. HOW TO EVALUATE A NEW TREATMENT  

               Is it safe?
               Does it really work? 

     

    GLOSSARY 

    INDEX

  • War Against the Germs: Epidemics, Microorganisms, and Biowarfare

    by Stephen Goldberg, M.D.,

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    The information contained in War Against the Germs: Epidemics, Microorganisms, and Biowarfare, will interest the medical, nursing, and PA clinical practitioners, as well as the knowledgeable public who would like a broad overview of the problems and ways to overcome pandemics.

    The prospects for pandemics have increased with rising population, closeness, travel, and the real possibility of laboratory leaks or purposeful attack. War Against the Germs discusses the kinds of microorganisms, including COVID, that have caused past epidemics and may take part in future ones (whether naturally or artificially created), the strengths and weaknesses of the microorganisms in causing disease, and our potential weapons against them―the immune system, antimicrobial drugs, immunizations, isolation, testing, and government and social measures.

    • Pages: 92
    • Publication: Edition 1 (August 9, 2022)
    • Language: English
    • ISBN: 9781935660637

    About the Authors

    Stephen Goldberg, M.D.

    Stephen Goldberg, M.D., a graduate of the Albert Einstein College of Medicine, is a researcher, physician, teacher, computer programmer, writer, musician/composer, and past President of the Medmaster Publishing Company for 40 years. Dr. Goldberg has published numerous medical and scientific papers through research at the Albert Einstein College of Medicine, National Institutes of Health, New York Medical College and the University of Miami School of Medicine. He has authored 20 books in a diversity of medical areas, including textbooks of Anatomy, Physiology, Biochemistry, Genetics, Biostatistics and Epidemiology, Neurology, Consciousness, Ophthalmology, Hematology, and Computer Programming, as well as many interactive computer programs on various medical topics, including Atlas of Microbiology and Atlas of Human Diseases. He is Professor Emeritus at the University of Miami Miller School of Medicine, where he taught medical students for 25 years. His reputation is that of an educator who can simplify complex topics. He received the George Paff Most Outstanding Professor Teaching Award11 times at the U of M and was invited in 2004 to be the keynote speaker at the medical school graduation commencement at the Washington University School of Medicine in St. Louis for his work in medical education. He is currently Editor-in-Chief of the Medmaster Publishing Company. 

    The information contained in War Against the Germs: Epidemics, Microorganisms, and Biowarfare, will interest the medical, nursing, and PA clinical practitioners, as well as the knowledgeable public who would like a broad overview of the problems and ways to overcome pandemics.

    The prospects for pandemics have increased with rising population, closeness, travel, and the real possibility of laboratory leaks or purposeful attack. War Against the Germs discusses the kinds of microorganisms, including COVID, that have caused past epidemics and may take part in future ones (whether naturally or artificially created), the strengths and weaknesses of the microorganisms in causing disease, and our potential weapons against them―the immune system, antimicrobial drugs, immunizations, isolation, testing, and government and social measures.

    • Pages: 92
    • Publication: Edition 1 (August 9, 2022)
    • Language: English

    About the Authors

    Stephen Goldberg, M.D.

    Stephen Goldberg, M.D., a graduate of the Albert Einstein College of Medicine, is a researcher, physician, teacher, computer programmer, writer, musician/composer, and past President of the Medmaster Publishing Company for 40 years. Dr. Goldberg has published numerous medical and scientific papers through research at the Albert Einstein College of Medicine, National Institutes of Health, New York Medical College and the University of Miami School of Medicine. He has authored 20 books in a diversity of medical areas, including textbooks of Anatomy, Physiology, Biochemistry, Genetics, Biostatistics and Epidemiology, Neurology, Consciousness, Ophthalmology, Hematology, and Computer Programming, as well as many interactive computer programs on various medical topics, including Atlas of Microbiology and Atlas of Human Diseases. He is Professor Emeritus at the University of Miami Miller School of Medicine, where he taught medical students for 25 years. His reputation is that of an educator who can simplify complex topics. He received the George Paff Most Outstanding Professor Teaching Award11 times at the U of M and was invited in 2004 to be the keynote speaker at the medical school graduation commencement at the Washington University School of Medicine in St. Louis for his work in medical education. He is currently Editor-in-Chief of the Medmaster Publishing Company. 

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