Preface
Chapter 1. Introduction
Chapter 2. The Cellular Components of Blood
Chapter 3. The Complete Blood Count (CBC)
Red Blood Cell (RBC) Count
Hematocrit (Hct) and Hemoglobin (Hgb)
Mean Corpuscular Volume (MCV)
Red Cell Distribution Width (RDW)
Iron
Ferritin
Total Iron Binding Capacity (TIBC)
Reticulocyte Count
White Blood Cell (WBC) Count
Neutrophil Count
Lymphocyte Count
Eosinophil Count
Monocyte Count
Basophil Count
Platelet Count
Atypical Cells
Atypical Platelets
Nonspecific Tests
Chapter 4. Red Blood Cells
Anemia
General Symptoms and Signs of Anemia
Causes of Anemia
History in Anemia
Physical Exam in Anemia
Iron Deficiency Anemia
B12/Folate Deficiency (Megaloblastic) Anemia
Anemia of Chronic Disease (ACD)
Hemolytic Anemias
Causes of Hemolytic Anemia
Sickle Cell Disease
Thalassemia
RBC Energy Pathway Disease
Red Cell Membrane Disease
Hemolytic Porphyria
Autoimmune Hemolytic Anemias
Sideroblastic Anemia
Aplastic Anemia
Iron Overload: Hemosiderosis/Hemochromatosis
Polycythemia
Chapter 5. Platelets and Blood Clotting
Platelet Function
The Blood-Clotting Cascade
Coagulation Tests
Clinical Disorders of Clotting
Problems with Platelets
Problems with the Clotting Cascade
Treatment of Bleeding Disorders
Excessive Clotting
Treatment of Clotting Disorders
Chapter 6. White Blood Cells and the Immune system
Natural (innate) Immunity
Molecules of Natural Immunity
Cells of Natural Immunity
Adaptive (acquired) Immunity
Humoral (antibody-mediated) Immunity: B Lymphocytes
Cell-mediated Immunity: T Lymphocytes
Immune Complexes
When Things Go Wrong
Microorganism Adaptation
Insufficient Immune Response
Excessive Immune Response
Autoimmunity
AIDS
Treatment: Immunosuppression and Immunostimulation
Chapter 7. Leukemia
Types of Leukemia
Diagnosis of Leukemia
Treatment of Leukemia
Chapter 8. Multiple Myeloma
Diagnosis of Multiple Myeloma
Treatment of Multiple Myeloma
Chapter 9. Myeloproliferative Disorders and Myelodysplasia
Polycythemia Vera
Diagnosis of Polycythemia Vera
Treatment of Polycythemia Vera
Essential Thrombocythemia
Diagnosis of Essential Thrombocythemia
Treatment of Essential Thrombocythemia
Chronic Neutrophilic Leukemia
Diagnosis of Chronic Neutrophilic Leukemia
Treatment of Chronic Neutrophilic Leukemia
Chronic Eosinophilic Leukemia
Diagnosis of Chronic Eosinophilic Leukemia
Treatment of Chronic Eosinophilic Leukemia
Myelofibrosis
Diagnosis of Myelofibrosis
Treatment of Myelofibrosis
Myelodysplasia
Diagnosis of Myelodysplasia
Treatment of Myelodysplasia
Systemic Mastocytosis
Diagnosis of Systemic Mastocytosis
Treatment of Systemic Mastocytosis
Chapter 10. Lymphoma
Hodgkin and Non-Hodgkin Lymphomas
Diagnosis of Lymphoma
Treatment of Lymphoma
Chapter 11. Splenomegaly
Function of the Spleen
Causes of Splenomegaly
Treatment of Splenomegaly
Chapter 12. Blood Transfusion
Transfusion and Grouping
A-B-O Factors
Rh Factor
Kinds of Blood Transfusions
Transplantation
Index
