TABLE OF CONTENTS

PART I. BASIC IMMUNOLOGY

CHAPTER 1. THE WORLD OF THE IMMUNE SYSTEM -- Innate Immunity (Natural Killer Cells; Complement pathways) -- Adaptive Immunity (Humoral immunity; Antibodies; Molecular features of immunoglobulins; Cell-mediated immunity)
CHAPTER 2. LYMPHOCYTES AND ANTIGENS -- Antigen Recognition -- Major Histocompatibility Complex (MHC) -- MHC Polymorphism -- T Cells and Antigen-presenting Cell Interaction -- Antibody Production (Activation of B Cells; Interaction of B cells and T helper cells; Isotope switching)
CHAPTER 3. OTHER IMPORTANT COMPONENTS OF THE IMMUNE SYSTEM -- Eosinophils -- Basophils -- Mast Cells -- Cytokines (Classification of cytokines; Cytokines and disease)

PART II. CLINICAL IMMUNOLOGY

CHAPTER 4. HYPERSENSITIVITY -- Type I Hypersenstitivity Reaction (IgE-mediated) (Allergic rhinitis) -- Type II Hypersensitivity Reaction (Antibody-mediated) (Blood transfusion reaction) -- Type III Hypersensitivity Reaction (Immune complex-mediated) (Serum sickness) -- Type IV Hypersensitivity Reaction (Cell-mediated; Delayed type) (Mantoux reaction; Allergic contact dermatitis) -- Eosinophils and Disease (Eosinophilia) -- Mast Cells and Disease (Mastocytosis)
CHAPTER 5. AUTOIMMUNITY -- Central Tolerance: T Cells -- Peripheral Tolerance: T Cells -- Central and Peripheral Tolerance: B Cells -- Factors Predisposing to Autoimmunity -- Mechanisms of Autoimmunity -- Autoimmune Diseases (Diagnosis of autoimmune diseases; Hashimoto thyroiditis; Systemic lupus erythematosus; Rheumatoid arthritis; Sjogren syndrome; Scleroderma)
CHAPTER 6. COMMON DIAGNOSTIC TESTS -- In Vivo Testing (Prick skin testing; Intradermal testing; Provocative in vivo tests; Patch tests) -- In Vitro Testing (ELISA; Radioallergosorbent test; Western blotting; Precipitation; Agglutination; Direct and indirect immunofluorescence)
CHAPTER 7. IMMUNODEFICIENCY -- Primary Immunodeficiency (Immunodeficiency affecting adaptive immunity; Immunodeficiency affecting humoral immunity; X-linked agammaglobulinemia; Common variable immunodeficiency; IgA deficiency; Hyper immunoglobulin E syndrome; T cell deficiency; DiGeorge syndrome; Combined B and T cell deficiency; Ataxia telangiectasia) -- Secondary (Acquired) Immunodeficiency -- Diagnosis of Immunodeficiency (Workup for primary immunodeficiencies of the innate immune system; Workup for primary immunodeficiences of the adaptive immune system) -- Management of Immunodeficiency (Management of AIDS)
CHAPTER 8. VACCINATION -- Immune Response to Vaccination -- Types of Vaccines -- Characteristics of an Ideal Vaccine  -- Recommended Vaccines for Children and Adults (including Pneumococcal vaccine; Human papillomavirus vaccine; Shingles vaccine) -- Passive Immunotherapy (Primary immunodeficiency and the use of IVIG)
CHAPTER 9. TRANSPLANTATION -- Types of Grafts -- Graft Success -- Graft Rejection -- Graft-Versus-Host Disease -- Current Practices in Organ Transplantation
CHAPTER 10. TUMOR IMMUNOLOGY -- Classification of Malignant Tumors (Carcinogenesis) -- Risk and Predisposing Factors of Malignancies -- Immune Response to Tumors (Immune surveillance and immunoediting; Elimination; Equilibrium, Escape) -- Tumor Immunotherapy (Active immunotherapy; Passive immunotherapy)

Index